First thing to note is that this pump only goes up to 60psi on the gauge so it is not suitable for road bikes. Because of this you can fine tune pressures for mtb and fat bikes though which is what I was going for. The ABS-2 valve takes a bit to get used to but once you understand how it works it is really nice. Lezyne has a video that can show you how to use it.
Having both a 27.5 bike and a high-volume tire 29er the pressures I run are fairly low (14-15psi and 25-26 psi respectively). This pump is great for filling these large tires and getting the pressures exact. It still works great on my CX tires run in the 40-45psi range. I don't have have high-pressure road tires.