I bought these tires as a literal last-second emergency replacement of a damaged tire before a 200 mile epic event. The ride took place on open road pavement of all states of repair (everything from city streets to decaying farm road to gravel patches). I did the research, and these seemed to fit what I needed. And I was wrong.
The Cinturato tires wouldn't seat for me at home using a home compressor and Stan's. I ended up taking it to a local shop, who had to re-tape the rims because the tire bead tore up the old tubeless tape. On my test rides the tires felt sluggish, but I figured that once they got a little scuffed up on the road they'd roll a little faster. But when you're spending 25% more energy to just keep normal pace, it's going to hurt later on, and it did.
I did not finish the event, in part because the tires dense rolling resistance sapped so much energy from me. I had to aggressively pedal going downhill to fight the excessive tackiness of the rubber compound of the Cinturatos. Going uphill felt like pushing lead weights with glue under them. There were several times I had to literally stand on the pedals to start the bike rolling in my second-to-lowest gear. And to give an idea how much ahem grip the tires have? While rolling the bike by the handlebars, the tires picked up dry leaves and grass on the pavement.
There are some good points, once you get them rolling they do stay rubber side down, even on twisting and turning 7-10% descents. I had a lot of confidence taking 35MPH pavement downhills knowing my lint-roller Cinturatos would stick, but I also could feel the tires literally slowing me down on these downhill runs. They also show very little sign of wear for 100 miles, so I guess that's a good thing?
Pirelli says this is their go anywhere tire and I'm hard pressed to figure out where I could go with these. They're too smooth for anything but hero gravel, they're too sluggish on pavement, even at the widest 35mm they're too narrow for any off-road racing of any kind, and they're too dead feeling for anyone who likes to ride. The best I can figure is this is a practice tire, possibly in the same idea of resistance training? It might also be good for commuting, I would think these turtle-shell tires could deflect glass and nails all day.
Having run them with and without tubes, I'd probably suggest inner-tubes. They seem to not seal well tubeless and had to clean up a small puddle in my hotel room the night before the event. I also wouldn't run them low pressure, as a larger contact patch would only mean more drag as you pedal. Probably a good commuter tire, but definitely not a racing, gravel or adventure tire like Pirelli claims. Not unless you like to spend 25% of your energy fighting friction.
Thank you for your feedback.