I've tried most of the major brands of pedals, these are hands down the best. The double sided entry means no looking down or flicking the pedals over with your foot before you clip in. Tons of great float adjustment. The new aero cleats make it a lot easier to walk in. Only downside is the initial setup can take a while if you are unfamiliar with it. Another bonus, Speedplay sells an extender kit so you can move the cleats further back.
I had speedplay for 10 years and then decided to try the Shimano spd. I couldn't wait to get back to my speedplay fast enough. I love the built in cleat covers, keeps them from extra wear and no need to carry a pair of covers that adds more weight and takes up room.