Have ridden as far as 158 miles along with a couple other century rides in the past month since ordering these shoes to go with my Shimano Ultegra pedals. They've work great. No numbness or discomfort at all on the long rides. Had mountain bike pedals and shoes on my road bike before this so the switch has definitely resulted in more efficiency and faster ride speed. I commute daily in these and go for long rides on weekends. Also for road shoes, the heal allows for walking without too much risk of slipping, etc. Would definitely order these again when they wear out.
I ordered the same size as my old shoes from a different manufacturer and these Shimano shoes were too small. I returned and moved up a size and these are perfect. The boa allows for perfect adjustments. Very comfortable.