I'm 6-0, 160, 32.5 waist. Ordered these in M size and they were simply too tight for comfort. I have other Castelli shorts (club kit) that I like so this isn't about the quality. I ordered some Assos shorts at the same time and decided to stick with them.
I used these shorts on a long climb and several short rides thus far. The pudding is more than sufficient. the waist seems a bit tight at first, but it not a discomfort. the shorts fit well. i have both hand washed and machine washed. on both occasions I let them air dry, they dried overnight no problem - good for multi day riding. these are my first good brandexpensive shorts and I like them very much. Very comfortable overall. I like the cuffs, adhere well to the thighs but soft.
I choice in bike shorts is a long inseam and supportive material. Although I was initially not fond of the mesh-lice frabric in the legs, it is holding up well after 50 plus rides and washing. I am careful not to dry in the dryer. I am happy with these shorts and other than the lighter material on the sides I would highly recommend.