I'm 170# and 5'9" the medium size was perfect. After 2 rides at 100+ miles I'm very pleased. Nice compression and no saddle problems or pain. The best of my now 4 Assos cycling shorts.
These are very comfortable. Easily the best bibs I have ever owned. I wish I had these when I completed my cross country trip a few years ago. Yes, they are quite expensive, but hold out for a sale and save a few bucks.